Mozilla Firefox (tested with 3.6.6) doesn't support border-radius, neither does Safari (4.0).
The vendor prefixes are still used by their respective vendors (WebKit and Mozilla Gecko) currently.
– Eric Jul 20 '10 at 19:10 There isn't a stable version of either layout engine that supports the prefix-less border-radius yet as far as I know. – BoltClock? Jul 20 '10 at 19:22.
It really just depends on the audience. It's new enough for the lines to still be a bit fuzzy. Check your user's browser statistics if it's at all possible - that's a much better guide than asking the general community because the community experience isn't necessarily going to match your users.
Even if all browsers supported border-radius (they don't see @Aircule's response), you may still want to carry the vender-specific code for legacy browser support. Firefox 3.5 will never support border-radius, even if Firefox 4.0 does. Of course, if your analytics indicate such browsers are irrelevant to your site, such code is unnecessary.
For reference, PPK keeps current a table of browser CSS3 browser support Also, if you want to keep your stylesheets light and easy to maintain, you can just use the border-radius property, and use Arron Gustafson's eCSStender JavaScript library to dynamically add -webkit- and -moz- extensions.
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